Dr Simon Puttick
CSIRO-AIBN Research Fellow
Australian Institute for Bioengineering and Nanotechnology
+61 7 33463849
Research Fellow in Molecular Imaging, AIBN (2013 – Present)
Research Associate, University of Cambridge (2012 – 2013)
PhD in Ionic Liquid Chemistry, University of Nottingham (2008 – 2011)
MSci in Chemistry, University of Nottingham (2004 – 2008)
Book Chapter
Fay, Mike, Bell, Chris, Dowson, Nick, Puttick, Simon and Rose, Stephen (2015). Imaging of brain tumours. Molecular considerations and evolving surgical management issues in the treatment of patients with a brain tumor. (pp. 235-276) edited by Dr. Terry Lichtor. Rijeka, Croatia: InTech Europe. doi: 10.5772/59981
Journal Articles
Genovesi, Laura A., Puttick, Simon, Millar, Amanda, Kojic, Marija, Ji, Pengxiang, Lagendijk, Anne K., Brighi, Caterina, Bonder, Claudine S, Adolphe, Christelle and Wainwright, Brandon J. (2020). Patient derived orthotopic xenograft models of Medulloblastoma lack a functional blood brain barrier. Neuro-Oncology. doi: 10.1093/neuonc/noaa266
Houston, Zachary H., Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B., Fletcher, Nicholas L., Fuchs, Adrian V., Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W., Mahler, Stephen M., Richards, Linda J., Caruso, Frank and Thurecht, Kristofer J. (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Central Science, 6 (5) acscentsci.9b01299, 727-738. doi: 10.1021/acscentsci.9b01299
Harrington, Brittney S., He, Yaowu, Khan, Tashbib, Puttick, Simon, Conroy, Paul J., Kryza, Thomas, Cuda, Tahleesa, Sokolowski, Kamil A., Tse, Brian W.C ., Robbins, Katherine K., Arachchige, Buddhika J., Stehbens, Samantha J., Pollock, Pamela M., Reed, Sarah, Weroha, S. John, Haluska, Paul, Salomon, Carlos, Lourie, Rohan, Perrin, Lewis C., Law, Ruby H. P., Whisstock, James C. and Hooper, John D. (2020). Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer. Theranostics, 10 (5), 2095-2114. doi: 10.7150/thno.30736
Brighi, Caterina, Reid, Lee, White, Alison L., Genovesi, Laura A., Kojic, Marija, Millar, Amanda, Bruce, Zara, Day, Bryan W., Rose, Stephen, Whittaker, Andrew K. and Puttick, Simon (2020). MR-guided focused ultrasound increases antibody delivery to nonenhancing high-grade glioma. Neuro-Oncology Advances, 2 (1), 1-12. doi: 10.1093/noajnl/vdaa030
White, Alison L., Langton, Christian, Wille, Marie-Luise, Hitchcock, James, Cayre, Olivier J., Biggs, Simon, Blakey, Idriss, Whittaker, Andrew K., Rose, Stephen and Puttick, Simon (2019). Ultrasound-triggered release from metal shell microcapsules. Journal of Colloid and Interface Science, 554, 444-452. doi: 10.1016/j.jcis.2019.07.020
Lee, Michael D., Tong, Wing Yin, Nebl, Thomas, Pearce, Lesley A., Pham, Tam M., Golbaz-Hagh, Arghavan, Puttick, Simon, Rose, Stephen, Adams, Timothy E. and Williams, Charlotte C. (2019). Dual site-specific labeling of an antibody fragment through sortase A and π-clamp conjugation. Bioconjugate Chemistry, 30 (10), 2539-2543. doi: 10.1021/acs.bioconjchem.9b00639
Lim, Malcolm, Puttick, Simon, Houston, Zachary H., Thurecht, Kristofer J., Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E., Jeffree, Rosalind L., Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R. and Saunus, Jodi M. (2019). Innovative therapeutic strategies for effective treatment of brain metastases. International Journal of Molecular Sciences, 20 (6) 1280, 1280. doi: 10.3390/ijms20061280
Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Smith, Fiona, Stringer, Brett, Carrington, Benjamin, Fuchs, Adrian, Bell, Craig, Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer, Boyd, Andrew and Day, Bryan (2018). EphA3 pay-loaded antibody therapeutics for the treatment of glioblastoma. Cancers, 10 (12) 519, 519. doi: 10.3390/cancers10120519
Tasker, Alison, Sainsbury, Frank and Puttick, Simon (2018). Particle-stabilized fluid-fluid interfaces: the impact of core composition on interfacial structure. Frontiers in Chemistry, 6 (AUG) 383, 383. doi: 10.3389/fchem.2018.00383
Clarke, Coby J., Puttick, Simon, Sanderson, Thomas J., Taylor, Alasdair W., Bourne, Richard A., Lovelock, Kevin R J. and Licence, Peter (2018). Thermal stability of dialkylimidazolium tetrafluoroborate and hexafluorophosphate ionic liquids: ex situ bulk heating to complement in situ mass spectrometry. Physical Chemistry Chemical Physics, 20 (24), 16786-16800. doi: 10.1039/c8cp01090k
Moonshi, Shehzahdi S., Zhang, Cheng, Peng, Hui, Puttick, Simon, Rose, Stephen, Fisk, Nicholas M., Bhakoo, Kishore, Stringer, Brett W., Qiao, Greg G., Gurr, Paul A. and Whittaker, Andrew K. (2018). A unique 19F MRI agent for the tracking of non phagocytic cells in vivo. Nanoscale, 10 (17), 8226-8239. doi: 10.1039/c8nr00703a
Tasker, Alison L., Puttick, Simon, Hitchcock, James, Cayre, Olivier J., Blakey, Idriss, Whittaker, Andrew K. and Biggs, Simon (2018). A two-step synthesis for preparing metal microcapsules with a biodegradable polymer substrate. Journal of Materials Chemistry B: Materials for Biology and Medicine, 6 (14), 2151-2158. doi: 10.1039/c8tb00348c
Brighi, Caterina, Puttick, Simon, Rose, Stephen and Whittaker, Andrew K. (2018). The potential for remodelling the tumour vasculature in glioblastoma. Advanced Drug Delivery Reviews, 136-137, 49-61. doi: 10.1016/j.addr.2018.10.001
Sinha, Sougata, Tong, Wing Yin, Williamson, Nathan H., McInnes, Steven J. P., Puttick, Simon, Cifuentes-Rius, Anna, Bhardwaj, Richa, Plush, Sally E. and Voelcker, Nicolas H. (2017). Novel Gd-Loaded Silicon Nanohybrid: A Potential Epidermal Growth Factor Receptor Expressing Cancer Cell Targeting Magnetic Resonance Imaging Contrast Agent. ACS Applied Materials and Interfaces, 9 (49), 42601-42611. doi: 10.1021/acsami.7b14538
Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Han, Yanxiao, Puttick, Simon, Peng, Hui, Magoling, Bryan John Abel, Reid, James C., Bernardi, Stefano, Searles, Debra J., Král, Petr and Whittaker, Andrew K. (2017). PFPE-Based Polymeric 19F MRI Agents: A New Class of Contrast Agents with Outstanding Sensitivity. Macromolecules, 50 (15), 5953-5963. doi: 10.1021/acs.macromol.7b01285
Ku, Kuan-Lin, Grøndahl, Lisbeth, Dao, Hui, Du, Ke, Puttick, Simon, Lai, Po-Liang, Peng, Hui, Chu, I-Ming and Whittaker, Andrew K. (2017). In vitro degradation study of polyanhydride copolymers / surface grafted hydroxyapatite composites for bone tissue application. Polymer Degradation and Stability, 140, 136-146. doi: 10.1016/j.polymdegradstab.2017.04.021
Bell, Christopher, Puttick, Simon, Rose, Stephen, Smith, Jye, Thomas, Paul and Dowson, Nicholas (2017). Design and utilisation of protocols to characterise dynamic PET uptake of two tracers using basis pursuit. Physics in Medicine and Biology, 62 (12), 4897-4916. doi: 10.1088/1361-6560/aa6b44
Dowson, Nicholas, Baker, Charles, Thomas, Paul, Smith, Jye, Puttick, Simon, Bell, Christopher, Salvado, Olivier and Rose, Stephen (2017). Federated optimisation of kinetic analysis problems. Medical Image Analysis, 35, 116-132. doi: 10.1016/j.media.2016.06.019
Zhang, Cheng, Moonshi, Shehzahdi Shebbrin, Peng, Hui, Puttick, Simon, Reid, James, Bernardi, Stefano, Bernhardt, Debra J. and Whittaker, Andrew K. (2016). Ion-responsive 19F MRI contrast agents for the detection of cancer cells. ACS Sensors, 1 (6), 757-765. doi: 10.1021/acssensors.6b00216
Zhang, Cheng, Peng, Hui, Li, Wen, Liu, Lianxiao, Puttick, Simon, Reid, James, Bernardi, Stefano, Searles, Debra J., Zhang, Afang and Whittaker, Andrew K. (2016). Conformation transitions of thermoresponsive dendronized polymers across the lower critical solution temperature. Macromolecules, 49 (3), 900-908. doi: 10.1021/acs.macromol.5b02414
Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2016). Multifunctional hyperbranched polymers for CT/19F MRI bimodal molecular imaging. Polymer Chemistry, 7 (5), 1059-1069. doi: 10.1039/c5py01707f
Bell, Christopher, Dowson, Nicholas, Puttick, Simon, Gal, Yaniv, Thomas, Paul, Fay, Mike, Smith, Jye and Rose, Stephen (2015). Increasing feasibility and utility of 18F-FDOPA PET for the management of glioma. Nuclear Medicine and Biology, 42 (10), 788-795. doi: 10.1016/j.nucmedbio.2015.06.001
Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2015). Segmented Highly Branched Copolymers: Rationally Designed Macromolecules for Improved and Tunable 19F MRI. Biomacromolecules, 16 (9), 2827-2839. doi: 10.1021/acs.biomac.5b00800
Puttick, Simon, Stringer, Brett W., Day, Bryan W., Bruce, Zara C., Ensbey, Kathleen S., Mardon, Karine, Cowin, Gary J., Thurecht, Kristofer J, Whittaker, Andrew K., Fay, Michael, Boyd, Andrew W. and Rose, Stephen (2015). EphA2 as a Diagnostic Imaging Target in Glioblastoma: A Positron Emission Tomography/Magnetic Resonance Imaging Study. Molecular Imaging, 14 (6), 385-395. doi: 10.2310/7290.2015.00008
Zhang, Cheng, Peng, Hui, Puttick, Simon, Reid, James, Bernardi, Stefano, Searles, Debra J. and Whittaker, Andrew K. (2015). Conformation of Hydrophobically Modified Thermoresponsive Poly(OEGMA-co-TFEA) across the LCST Revealed by NMR and Molecular Dynamics Studies. Macromolecules, 48 (10), 3310-3317. doi: 10.1021/acs.macromol.5b00641
Bell, Christopher, Dowson, Nicholas, Fay, Mike, Thomas, Paul, Puttick, Simon, Gal, Yaniv and Rose, Stephen (2015). Hypoxia imaging in gliomas with 18F-fluoromisonidazole PET: toward clinical translation. Seminars in Nuclear Medicine, 45 (2), 136-150. doi: 10.1053/j.semnuclmed.2014.10.001
Puttick, Simon, Bell, Christopher, Dowson, Nicholas, Rose, Stephen and Fay, Michael (2015). PET, MRI and simultaneous PET/MRI in the Development of Diagnostic and Therapeutic Strategies for Glioma. Drug Discovery Today, 20 (3), 306-317. doi: 10.1016/j.drudis.2014.10.016
Puttick, Simon, Boase, Nathan R. B., Blakey, Idriss and Thurecht, Kristofer J. (2014). Imaging tumour distribution of a polymeric drug delivery platform in vivo by PET-MRI. Journal of Chemical Technology and Biotechnology, 90 (7), 1237-1244. doi: 10.1002/jctb.4489
Bell, Christopher, Rose, Stephen, Puttick, Simon, Pagnozzi, Alex, Poole, Christopher M., Gal, Yaniv, Thomas, Paul, Fay, Michael, Jeffree, Rosalind L. and Dowson, Nicholas (2014). Dual acquisition of (18)F-FMISO and (18)F-FDOPA. Physics in Medicine and Biology, 59 (14), 3925-3949. doi: 10.1088/0031-9155/59/14/3925
Buonincontri, Guido, Wood, Nigel I., Puttick, Simon G., Ward, Alex O., Carpenter, T. Adrian, Sawiak, Stephen J. and Morton, A. Jennifer (2014). Right Ventricular Dysfunction in the R6/2 Transgenic Mouse Model of Huntington's Disease is Unmasked by Dobutamine. Journal of Huntington's Disease, 3 (1), 25-32. doi: 10.3233/JHD-130083
Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2014). Biodegradable core crosslinked star polymer nanoparticles as 19F MRI contrast agents for selective imaging. Polymer Chemistry, 5 (5), 1760-1771. doi: 10.1039/c3py01311a
Wang, Kewei, Peng, Hui, Thurecht, Kristofer J., Puttick, Simon and Whittaker, Andrew K. (2013). pH-responsive star polymer nanoparticles: potential F-19 MRI contrast agents for tumour-selective imaging. Polymer Chemistry, 4 (16), 4480-4489. doi: 10.1039/c3py00654a
Puttick, Simon, Davis, Adrienne L., Butler, Kevin, Irvine, Derek J., Licence, Peter and Thurecht, Kristofer J. (2013). The influence of domain segregation in ionic liquids upon controlled polymerisation mechanisms: RAFT polymerisation. Polymer Chemistry, 4 (5), 1337-1344. doi: 10.1039/C2PY20835K
Taylor, Alasdair W., Puttick, Simon and Licence, Peter (2012). Probing solvation in ionic liquids via the electrochemistry of the DPPH radical. Journal of the American Chemical Society, 134 (38), 15636-15639. doi: 10.1021/ja3052816
Boatwright, Adrian L., Puttick, Simon and Licence, Peter (2011). Can a siphon work in vacuo?. Journal of Chemical Education, 88 (11), 1547-1550. doi: 10.1021/ed2001818
Puttick, Simon, Davis, Adrienne L., Butler, Kevin, Lambert, Lynette, El Harfi, Jaouad, Irvine, Derek J., Whittaker, Andrew K., Thurecht, Kristofer J. and Licence, Peter (2011). NMR as a probe of nanostructured domains in ionic liquids : Does domain segregation explain increased performance of free radical polymerisation?. Chemical Science, 2 (9), 1810-1816. doi: 10.1039/c1sc00207d
Puttick, Simon, Irvine, Derek J., Licence, Peter and Thurecht, Kristofer J. (2009). RAFT-functional ionic liquids: towards understanding controlled free radical polymerisation in ionic liquids. Journal of Materials Chemistry, 19 (18), 2679-2682. doi: 10.1039/b817181p
Conference Papers
Offenhauser, Carolin, Carrington, Benjamin, Thurecht, Kris, Ensbey, Kathleen, Bruce, Zara, Jamieson, Paul, Lim, Yi Chieh, Akgul, Seckin, Li, Michelle, Stringer, Brett, Puttick, Simon, Fuchs, Adrian, Picard, Daniel, Ingram, Wendy, Hallahan, Andrew, Moore, Andrew, Johns, Terrance, Gottardo, Nicholas, Remke, Marc, Boyd, Andrew and Day, Bryan (2018). EPHA3 A NOVEL TUMOUR SPECIFIC THERAPEUTIC TARGET FOR MEDULLOBLASTOMA. 18th International Symposium on Pediatric Neuro-Oncology (ISPNO), Denver Co, Jun 30-Jul 03, 2018. CARY: OXFORD UNIV PRESS INC.
Puttick, S., Dowson, N., Fay, M., Bell, C., Martin, J. and Rose, S. (2016). Effect of Ligand Size On Uptake Andwashout of Epha2 Targeted Theranostics From Glioblastomas Using 64Cu-Pet. 27th International Symposium on Cerebral Blood Flow, Metabolism and Function / 12th International Conference on Quantification of Brain Function with PET, Vancouver, BC, Canada, Jun 27-30, 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0271678X16639008
Zhang, Cheng, Wang, Kewei, Thurecht, Kris, Puttick, Simon, Peng, Hui and Whittaker, Andrew (2015). Solution properties of EOGMA-containing macromolecules. 4th Federation of Asian Polymer Societies – International Polymer Congress, Kuala Lumpur, Malaysia, 5-8 October 2015. Weinheim, Germany:
Puttick, Simon, Stringer, Brett W., Day, Bryan W., Mardon, Karine, Cowin, Gary J., Fay, Michael, Thurecht, Kristofer J., Whittaker, Andrew K., Boyd, Andrew W. and Rose, Stephen (2014). EphA2 as a diagnostic imaging target in glioblastoma: A PET/MRI study. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, 05-09 April 2014. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-LB-12
Thurecht, Krisofer J., Puttick, Simon, Irvine, Derek J. and Licence, Peter (2009). POLY 252-RAFT-functional ionic liquids: Controlled free radical polymerization in ionic liquids. American Chemical Society National Meeting, Salt Lake City, UT, U.S.A., 22 -26 March 2009. Washington, DC United States: American Chemical Society.